Breakthrough in heart technology: prototype of first soft robotic artificial heart

An international team of researchers with AMOLF group leader Bas Overvelde, has taken the first steps towards developing a new type of artificial heart that combines soft robotics with advanced biomaterials. This so-called ‘Hybrid Heart’ has been published in the journal Nature Communications on June 3rd.

A new hope for heart failure patients

The Hybrid Heart is designed for patients suffering from end-stage heart failure and represents a promising alternative to existing artificial hearts, which are often associated with serious complications. The new technology mimics the natural heartbeat through a soft robotic “muscle” (septum) and uses flexible fabric materials. This allows for a much more natural simulation of blood flow compared to current artificial heart devices. The first prototype of the heart has been evaluated in an animal experiment.

AMOLF soft robotics

The Soft Robotic Matter group at AMOLF has been involved in developing and analyzing the shape and mechanics that enable the Hybrid Heart to move. While a natural heart pumps blood using muscle contractions, the Hybrid Heart relies on air pressure to contract artificial muscles that then cause blood to circulate.

Sputtering ketchup bottle

One of the major challenges Bas and his colleagues face, is creating a heartbeat with limited use of electronics and software, with the goal to increase the overall reliability of the device. A promising solution may lie in a mechanism inspired by the valve of a ketchup bottle.

Bas: “The valve allows you to easily control the amount of ketchup dispensed and prevents leakage. But when you turn the bottle upside down and squeeze it wrong, the ketchup sometimes sputters and makes a mess.” This sputtering occurs when the valve opens and closes rapidly in succession.

Bas and his team have redesigned this valve to work with the required pressures and flows to power the pneumatic artificial muscle, and have demonstrated the potential to let the Hybrid Heart beat using a constant airflow from the valve.

To hear more about the hybrid heart project, listen to BNR Beter podcast interview with Bas Overvelde and Jolanda Kluin (Erasmus MC): https://www.bnr.nl/podcast/beter/10577037/hybride-hart-zachte-robot-als-oplossing-bij-hartfalen

Video

Reference
Maziar Arfaee, Annemijn Vis, Paul A.A. Bartels, Lucas C. van Laake, Lucrezia Lorenzon, Dina M. Ibrahim, Debora Zrinscak, Anthal I.P.M. Smits, Andreas Henseler, Matteo Cianchetti, Patricia Y.W. Dankers, Carlijn V.C. Bouten, Johannes T.B. Overvelde, Jolanda Kluin, A soft robotic total artificial Hybrid Heart, Nature Communications, 16, 3 June (2025).

What's happening

Most recent news items

All news items

Collaboration

Successful outcomes of international EBEAM program led by AMOLF

The EU Pathfinder project Electron Beams Enhancing Analytical Microscopy (EBEAM) that was recently completed has received a highly positive review of the European Innovation Council (EIC). EBEAM brought together eight European research institutions and companies, including AMOLF, that develop new concepts and instruments combining spectroscopic analysis with electron microscopy.

Read news item

Research highlights

Everything you need to know about organoids

Organoids are instrumental in improving our understanding of processes that are otherwise hidden inside the body. For instance, these small 3D organs can be used to test medicines on tissue grown from a patient’s own cells. AMOLF researchers carry out unique and complex experiments to follow organoids in time. In order to enable other researchers to benefit from their experiences, they now publish their methods in the prestigious journal Nature Protocols.

Read news item

Events and outreach

Minister Rianne Letschert wears hat and shoulder ornament inspired by Wim Noorduin’s research

This year at the opening of the parliamentary year (Prinsjesdag) Minister of Education, Culture and Science Rianne Letschert wears a spectacular hat and shoulder ornament. Both of them are inspired by the microscopic structures studied by group leader Wim Noorduin (AMOLF/UvA), which look remarkably like tiny flowers under a microscope. Artist and designer Malou Beemer translated these shapes, normally invisible to the naked eye, into wearable art.

Read news item

Nachi Stern, Group Leader Learning Machines at AMOLF

People and recognition

Nachi Stern awarded ERC Starting Grant to explore how matter learns

Why do brains learn, but rocks do not? Could a material one day adapt to its environment the way a living organism does? AMOLF group leader Dr. Nachi Stern has been awarded an ERC Starting Grant to investigate the physical laws of learning, in a project called, “Physical Learning in Dynamical Systems.”

Read news item