Biochemical Networks

Group leader: Prof. dr. Pieter Rein ten Wolde

Biochemical networks are the central processing units of life. They can perform a variety of computational tasks analogous to electronic circuits. Their design
principles, however, are markedly different: in a biochemical network,computations are performed by molecules that chemically and physically interact with each other. The aim of the Biochemical Networks group and group leader Pieter Rein ten Wolde is to unravel their design principles using a combination of database analyses, theory and computer simulation. read more >>

Recent highlight

How can cells transmit the myriad environmental cues to which they are exposed in an efficient and reliable manner? Researchers from the FOM Institute AMOLF have shown that cells, like computers, can multiplex: cells can transmit multiple signals simultaneously via a single information path without these signals disrupting one another (Wiet de Ronde, Filipe Tostevin, and Pieter Rein ten Wolde, Phys. Rev. Lett. 107, 048101 (2011)) read more >>

Laymen introduction (in Dutch)

Snapshot of a simulation of a signal transduction pathway (MAPK)

Snapshot of a simulation of a signal transduction pathway (MAPK). The Biochemical Network group develops and applies new numerical techniques that make it possible to simulate biochemical networks at the particle level in time and space.