Recently it has become possible to follow the folding of a single protein using single-molecule techniques. However, folding pathways are generally studied for isolated proteins, even though interactions with chaperones are known...

Our lab employs simple experimental model systems to study fundamental evolutionary processes, using concepts from biology, engineering, and physics

Large families of transcription factors, which regulate gene expression by binding to DNA, have been formed by gene duplications and mutational divergence. You will measure this cross-repression within the lac repressor family,...