Group leader: Prof. dr. Sander Tans

Understanding the dynamics and evolution of biomolecular networks is a central problem in biology. From a physics perspective, these topics present many intriguing open questions: Can one follow evolutionary trajectories step-by-step? What constrains these trajectories? Selective pressures are not constant, which is particularly relevant for regulatory functions. How does this correlate with mutational steps? Does gene expression noise affect fitness?

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