Research Activities Biomolecular Photonics

We will use transient two-dimensional infrared spectroscopy to probe biomolecular dynamics on timescales ranging from femtoseconds to milliseconds. This technique allows one to measure the relative distances and orientations of chemical groups, as well as providing information about the mobilities of the groups (see figure). We will, for example, study how the hydrogen bonds that hold together peptide chains in a protein break and reform, and how this allows different amino-acid residues to move with respect to each other.

Part of the research is devoted to the development of strategies to increase the sensitivity of the nonlinear spectroscopic experiments. We plan to achieve this by using concepts from nanophotonics, such as nano-antennas for field enhancement.

Conformational dynamics with 2DIR

There are projects for PhD-students and master students:
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