Research activities Biochemical Networks

The main research areas of the Biochemical Networks group and group leader Pieter Rein ten Wolde are:

Development new computational techniques
In the past years, we have developed two new numerical techniques:

• Forward Flux Sampling (FFS)
  FFS is a technique that allows the efficient simulation of rare events in both equilibrium and non-equilibrium systems. Read more >>

• Green’s Function Reaction Dynamics (GFRD)
  GFRD is an algorithm that makes it possible to simulate reaction-diffusion systems at the particle level. Read more >>

Rare events in biochemical networks
Rare events are the rare, but important, switching events between different stationary states of a biochemical network. Read more >>

Spatio-temporal correlations in biochemical networks
Spatio-temporal fluctuations of the network components can strongly affect the dynamics of biochemical networks. Read more >>

Circadian oscillations
Circadian oscillations are oscillations of biochemical networks with a period of 24 hours. They are the clocks that living cells use to anticipate the changes between day and night. Read more >>

Costs and benefits of biochemical noise
How do protein concentration fluctuations affect the fitness of an organism?
Read more >>