AMOLF research on the covers of two prestigious journals

The February 20 cover of Science features the work of AMOLF-group leader Sander Tans.

The cover image illustrates how the folding pathway of a protein (MBP, transparent) is altered by a chaperone (SecB, yellow), which was revealed for the first time (Science 318, 1458-61). Here MBP is shown suspended in its molten globule state and destined for transport across the cellular membrane. The research was a collaboration with Arnold Driessen (Groningen University). This work was chosen to highlight the upcoming Gordon Research Conferences.

Last week, another AMOLF research topic graced the cover of another journal; Macromolecular Ion Physics' Postdoc Luke MacAleese's article on the perspective of imaging mass spectrometry on tissue proteomics was featured on the cover of Proteomics.

Science cover February 20th. Image credits: Graham Johnson (The Scripps Institute, www.fivth.com), Sander Tans (AMOLF)

Cover of Proteomics, 4'09