The aim of this project is to unravel how ATP-driven chaperones assist the folding of single protein chains, using optical tweezers.read more »

Large families of transcription factors, which regulate gene expression by binding to DNA, have been formed by gene duplications and mutational divergence. You will measure this cross-repression within the lac repressor family,...read more »

Our lab employs simple experimental model systems to study fundamental evolutionary processes, using concepts from biology, engineering, and physicsread more »